Contents

• List of Figures
• List of Tables
• 1 Inflammation
  • 1.1 Principles of inflammation
    • 1.1.1 The response to injury and infection
    • 1.1.2 Factors involved in cell damage
    • 1.1.3 The phases of inflammation
  • 1.2 Exudation and swelling
    • 1.2.1 Fluid exudate
    • 1.2.2 Cellular exudate
  • 1.3 Cells participating in inflammation
    • 1.3.1 Mast cells and basophils
    • 1.3.2 Eosinophils
    • 1.3.3 Neutrophils, central cells in acute inflammation
      • 1.3.3.1 Neutrophil granules
      • 1.3.3.2 Neutrophils in host defence
      • 1.3.3.3 Neutrophils and host tissue damage
      • 1.3.3.4 Free radicals produced by neutrophils
      • 1.3.3.5 Regulation of neutrophil function
    • 1.3.4 Macrophages and monocytes
      • 1.3.4.1 Heterogeneity and activation of macrophages
      • 1.3.4.2 Biological functions of macrophages
      • 1.3.4.3 The role of macrophages in angiogenesis
  • 1.4 Mediators of inflammation
    • 1.4.1 Histamine and serotonin
    • 1.4.2 Lipid mediators
    • 1.4.3 Products of the complement system
    • 1.4.4 The coagulation mechanism
    • 1.4.5 Fibrinolysis
    • 1.4.6 The kinin-forming system
    • 1.4.7 Cytokines mediating inflammatory and effector functions
      • 1.4.7.1 Chemokines
    • 1.4.8 Chemotactic factors
    • 1.4.9 The acute phase reactants
  • 1.5 Molecular mechanisms of the acute cell-mediated inflammatory reaction
    • 1.5.1 Adhesion molecules
    • 1.5.2 Leukocyte mobility and chemotaxis
  • 1.6 Categories of inflammation mediated by the immune system
    • 1.6.1 Allergic (reaginic) acute inflammation
    • 1.6.2 Acute inflammation mediated by cytotoxic antibodies
    • 1.6.3 Acute inflammation mediated by immune complexes
    • 1.6.4 Chronic inflammation (delayed-type of hypersensitivity reaction)
• 2 Fever
  • 2.1 Regulation and control of body temperature
  • 2.2 Pathogenesis of fever
  • 2.3 Causes of fever
  • 2.4 Progress of the fever and accompanying symptoms
  • 2.5 Fever from the clinical point of view
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